Registered Nurse Jobs in South Carolina

Browse 827 registered nurse jobs in South Carolina. Updated daily with salary data and direct application links.

827 jobs
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Registered Nurse, RN- Pediatrics
BAYADA Home Health Care · $62k - $67k
Elgin, SC
2mo ago
B
RN - Weekend Shifts
BAYADA Home Health Care · Weekends · $62k - $67k
Lancaster, SC
2mo ago
Registered Nurse (RN) Care Manager — Roper Hospital — PRN
Roper St. Francis Healthcare · PRN
Charleston, SC
Registered Nurse (RN) Physician Practice — Occupational Medicine — Onsite Clinic
Roper St. Francis Healthcare · Days
Charleston, SC
Registered Nurse (RN) – Orthopedic Surgery – Med Surg – Bon Secours St. Francis Hospital
Roper St. Francis Healthcare · Days
Charleston, SC
Registered Nurse (RN) — Emergency Department (ED) — Roper Berkeley
Roper St. Francis Healthcare · Days
Summerville, SC
Registered Nurse (RN) — Oncology — Roper Hospital — Weekend Only
Roper St. Francis Healthcare · Weekends
Charleston, SC
Registered Nurse
Georgetown Hospital System
Murrells Inlet, SC
Registered Nurse (RN) - Staff/Med Surg II
Georgetown Hospital System · Nights
Georgetown, SC
Registered Nurse (RN) - Med Surg New to Practice - St. Francis Downtown
Bon Secours Mercy Health · Nights
Greenville, SC
Registered Nurse (RN) - Acute Care, Family Birthplace, PRN, Nights
Prisma Health-Upstate · PRN
Greenville, SC
Registered Nurse (RN)-Hospital Care Manager, Full-Time, Days
Prisma Health-Upstate · Days
Laurens, SC
Registered Nurse (RN)-Case Manager Hospital Case Mgmt, PRN, Days
Prisma Health-Midlands · PRN
Sumter, SC
Registered Nurse (RN) - Specialist Ambulatory Clinic, OB/GYN Clinic, Full-Time
Prisma Health-Upstate
Greenville, SC
Registered Nurse (RN) - Student Health Center, PRN, Day
Prisma Health-University Medical Group · PRN
Greenville, SC
Registered Nurse (RN) - Nurse Resident, September/October 2026, ICU
Prisma Health-Midlands
Sumter, SC
Registered Nurse (RN)-Acute Care, OR Pre-Op, PT, Day
Prisma Health-Upstate
Greenville, SC
Registered Nurse (RN) - Acute Care, Emergency Dept , Full Time, Night
Prisma Health-Upstate · Nights
Seneca, SC
Registered Nurse (RN) Outpatient Oncology Infusion, FT, Days
Prisma Health-Upstate · Days
Easley, SC
Registered Nurse
Georgetown Hospital System
Murrells Inlet, SC
Registered Nurse (RN) - Staff/Med Surg II
Georgetown Hospital System · Nights
Georgetown, SC
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RN, Same Day Surgery, Cheraw
Erym
Cheraw, SC
C
Care Transition Nurse (RN) — Population Health
Careers
Any city in South Carolina, SC
C
Registered Nurse (RN) - Nurse Resident, September/October 2026, ICU
Careers
Sumter, SC
C
Registered Nurse (RN) - Ambulatory Clinical Coordinator, OB/GYN Clinic, FT
Careers
Greenville, SC

About Registered Nurse Jobs in South Carolina

ScrubShifts aggregates registered nurse jobs in south carolina positions from 33 healthcare employers. Jobs are updated daily with salary data, full descriptions, and direct application links.

We track registered nurse positions in South Carolina from 33 healthcare employers.

Posted pay for these roles ranges from $22 to $156k, with a median near $62k (92 of the listings include salary).

Top Employers Hiring

Careers 383Eodr 122Bon Secours 101Erym 85BAYADA 50Bon Secours Mercy Health 10